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Standard Operating
Procedures

Standard Operating Procedures (SOP) are required by Occupational Safety & Health Administration’s (OSHA) laboratory standard section (1910.1450(e3i)) to be developed and maintained by individual laboratories. The Chemical Hygiene Plan must contain “Standard Operating Procedures relevant to safety and health considerations to be followed when laboratory work involves the use of hazardous chemicals.” Laboratories in conjunction with Environmental Health and Safety (EHS) must perform a hazard assessment of the laboratory procedures to determine which SOPs must be developed. At a minimum a laboratory must have laboratory specific SOPs for the chemical and biological hazards and any agents which are used in approved animal studies.
Standard Operating Procedure Requirements
Any chemical which has a National Fire Protection Association (NFPA) Health Rating of 2 or above or has specific handling procedures or equipment should have an SOP developed for the specific use of those chemicals. One example of a chemical is Hydrofluoric Acid. Chemicals that are rated below or have similar handling requirements can be developed as a blanket SOP. Some common examples of a blanket SOPs include: flammable liquids and corrosives. SOPs should also be developed for any Risk Group 2 Biological Agent work that is performed in a laboratory.

An SOP must contain at a minimum the specific personal protective equipment required, engineering controls, decontamination procedures, waste disposal procedures and a description of the laboratory procedure that will be performed. EHS has developed an SOP template that is accessible on the EHS website. Some specific and blanket SOPs can also be found on the EHS website for the laboratories’ reference. Any SOP that is used from the EHS website must be modified for the laboratories’ specific procedures and policies.

SOPs must be housed in the laboratories’ Chemical Hygiene Plan and all employees must have access to the SOPs for the laboratory. The laboratory is responsible to train all employees on appropriate handling procedures for those chemical and biological hazards. SOPs should be reviewed annually to ensure that the entire document is updated with any procedural or location changes. New SOPs must be developed when a new hazard is presented in the laboratory.

All SOPs for the Laboratory and Animal Use must be uploaded and stored in the Chemical Hygiene Plan.

SOPs which are required for Animal Use Protocols (IACUC) Chemical Hygiene Plan Approvals can be found under Animal Research Safety.